A University of Calgary-led international research team has identified a genetic factor that may explain why people respond so differently to opioid pain medications, and why some individuals face ...

Explore the role of transcription factor biology in drug discovery and how it impacts our understanding of disease mechanisms ...

New research has uncovered more about the complexity of human gene regulation by identifying certain sequences of proteins called transcription factors that bind to DNA and regulate the expression of ...

A multi-institutional team of investigators have developed a catalog of transcription factor binding sites that regulate gene expression across the genome, according to a recent study published in ...

Many of the body's processes slow down or falter as we get older, including tissue regeneration. In a new study, researchers ...

Transcription factors are the most powerful genes in our body. They are master regulators and have been implicated in our biggest diseases, even aging itself. Yet, many in the pharmaceutical industry ...

Researchers identified DMTF1 as a key transcription factor driving neural stem cell regeneration during aging. The study ...

Research into transcription factors deepen understanding of the 'language' of the genome, offering insights into human development. New research has uncovered more about the complexity of human gene ...

In biology classrooms, we often learn that genes are transcribed into mRNA, which is then translated into proteins—a tidy, linear process. But gene expression in living cells is far more intricate, ...