KRAS is the most frequently mutated oncogene across all human cancers. Although different KRAS mutations have long been thought to exert the same cancer-driving effects, a new study led by UT ...

In a recent study posted to the bioRxiv* preprint server, researchers analyzed the effects of mutations of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Omicron variant at the atomic ...

Researchers have created the first complete map showing how hundreds of mutations in a key cancer gene affect tumor growth. By testing every possible mutation in a critical hotspot, they found that ...

Cerebrospinal fluid circulating tumor DNA for the detection and characterization of leptomeningeal metastasis in non-small cell lung cancer. This is an ASCO Meeting Abstract from the 2023 ASCO Annual ...

HOUSTON ― Researchers from The University of Texas MD Anderson Cancer Center have discovered that grouping epidermal growth factor receptor (EGFR) mutations by structure and function provides an ...

Experiments from the 1940s established a key tenet of genetics—mutagenesis occurs randomly across the genome. New research, however, suggests that mutations may be less random than originally thought.

Fifteen studies comprising 594 patients were included. The most frequently observed uncommon solitary mutations were G719X in 25% (81/327) of patients and L861Q in 21% (69/327). The most common ...