T cells play central roles in the adaptive immune response against cancer. Their functional inactivation is a primary driver of tumor progression, making the reactivation of T cell function a main ...

Shimon Sakaguchi, an immunologist and a distinguished professor of Osaka University, attends a press conference after winning the 2025 Nobel Prize in medicine, in Suita, Osaka prefecture on October 6, ...

Researchers at Moffitt Cancer Center have developed a novel biomaterial-based system that induces the formation of tertiary ...

A study published in Science Advances shares new insights into how two of the most common types of chimeric antigen receptor (CAR) T cells kill cancer. Investigators from Baylor College of Medicine, ...

In 2006 immunologist and 2025 Nobel prize winner Shimon Sakaguchi co-wrote an article in Scientific American that now feels prophetic. In the story, entitled “Peacekeepers of the Immune System,” ...

A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...

Study sets stage for development of synthetic biosensors with custom-built sensing and responses for basic and translational cell engineering applications.