Biologists from the University of York (UK) have discovered enzymes that catalyze the biosynthesis of alkaloids in a number ...

Camptothecin is a monoterpene indole alkaloid (MIA) used to produce semisynthetic antitumor drugs. We investigated camptothecin synthesis in Camptotheca acuminata by combining transcriptome and ...

Since the early 1800s, practitioners of organic chemistry have been fascinated with a group of plant-derived compounds called "alkaloids." Alkaloids contain at least one nitrogen atom among other ...

Complex polycylic structures are found in nearly every biosynthetic class of natural products. In particular, an amazing range of rigid densely functionalized polycylic compounds are formed from ...

Barley is one of the most important cereal crops on a global scale. Many barley cultivars produce a toxic alkaloid called gramine that affects the suitability of barley as fodder, but also helps to ...

The red imported fire ant, Solenopsis invicta Buren (Hymenoptera: Formicidae), produces venom that consists of alkaloids and a small amount of protein. The venom possesses a diversity of bioactivities ...

Sequencing of single-agent (SA) docetaxel (T) and gemcitabine (G) therapy for patients (pts) with advanced non-small cell lung cancer (NSCLC): Results of three consecutive randomized trials ...

Pyrrolizidine alkaloids (PA) are natural constituents detected all over the world in more than 350 plant species and suspected to occur in more than 6,000. Plants produce them as a defence against ...

IN spite of the fact that modern fashions in chemical research have inclined towards the hormones and vitamins, much work has been accomplished during the past twenty years in the field of the plant ...