snmjournals.org

Pretargeted Imaging and Therapy

In vivo pretargeting stands as a promising approach to harnessing the exquisite tumor-targeting properties of antibodies for nuclear imaging and therapy while simultaneously skirting their ...
snmjournals.org

Utility of PSMA PET/CT After an Initial Negative Scan: Results from a Prospective Multicenter PSMA PET Registry

Journal of Nuclear Medicine April 2026, jnumed.126.272204; DOI: https://doi.org/10.2967/jnumed.126.272204 ...
snmjournals.org

Comparison of EORTC Criteria and PERCIST for PET/CT Response Evaluation of Patients with Metastatic Colorectal Cancer Treated with Irinotecan and Cetuximab

PET/CT performed with 18 F-FDG has become an established imaging modality in oncology (1,2). For several malignancies, including colorectal cancer, 18 F-FDG PET/CT examination is today recommended for ...
snmjournals.org

Standardization of Preclinical PET/CT Imaging to Improve Quantitative Accuracy, Precision, and Reproducibility: A Multicenter Study

The necessity for standardization in clinical PET/CT protocols was acknowledged and initiated nearly 20 y ago (1–4). This recognition mainly stemmed from multicenter trials focused on quantifying and ...
snmjournals.org

The Australian National Total-Body PET Facility—A Shared Resource and Risk Model for Implementing Total-Body PET

The introduction of total-body PET, or long–axial-field-of-view (LAFOV) PET, has led to high-quality imaging by improving sensitivity through its increased axial coverage and volume of detector ...
snmjournals.org

18 F-FDG Avidity in Lymphoma Readdressed: A Study of 766 Patients

PET/CT with 18F-FDG is an important noninvasive diagnostic tool for management of patients with lymphoma, and its use may surpass current guideline recommendations. The aim of the present study is to ...
snmjournals.org

Radioactive Iodine Therapy for Differentiated Thyroid Cancer: Lessons from Confronting Controversial Literature on Risks for Secondary Malignancy

There has been increasing focus on the side effects of radioactive iodine treatment (RAIT) given to patients with well-differentiated thyroid cancer (WDTC). The secondary malignancies evoke a ...
snmjournals.org

Molecular Imaging of Bone Metastases and Their Response to Therapy

Bone metastases are common, especially in more prevalent malignancies such as breast and prostate cancer. They cause significant morbidity and draw on health-care resources. Molecular and hybrid ...
snmjournals.org

Utility of FDG-PET/CT for Detection of Cardiovascular Implantable Electronic Device (CIED) Infections

Introduction: Infections in Cardiovascular Implantable Electronic Device (CIED) are complications that pose extreme health risks to patients with implants such as pacemakers and defibrillators.
snmjournals.org

Prediction of absorbed dose by tumors and critical organs after Lu-177-DOTATATE therapy using pretherapeutic Ga-68-DOTATOC PET/CT

Purpose: Lu-177-DOTATATE (Lutathera®), a type of peptide receptor radionuclide therapy (PRRT) targeting the somatostatin receptor (SSTR), has been shown effective in patients with metastatic ...
snmjournals.org

Utility of PSMA PET/CT in Staging and Restaging of Renal Cell Carcinoma: A Systematic Review and Metaanalysis

Journal of Nuclear Medicine May 2024, jnumed.124.267417; DOI: https://doi.org/10.2967/jnumed.124.267417 ...
snmjournals.org

Development of an Optimized CXCR4-Targeting Theranostic Pair

We developed a new C-X-C chemokine receptor 4 (CXCR4)–targeting radiolabeled peptide, [68Ga]Ga/[177Lu]Lu-BL34, using a novel and potent cyclic peptide based on structure–activity relationship studies ...