A novel epigenetic therapy has demonstrated activity against treatment-resistant acute myeloid leukaemia in preclinical ...

In part II of his conversation with Dr Nick Lynch, founder of Curlew Research, Raminderpal Singh asks the uncomfortable ...

A new review finds that next-generation BET-targeted therapies, including selective inhibitors and PROTACs, are addressing ...

Scientists at VCU Massey Comprehensive Cancer Center have developed an autophagy-targeting chimera that redirects cancer ...

A new review examines how advances in drug design, PROTAC degraders and combination therapies are reviving the clinical ...

A new review highlights how physical forces such as blood flow, breathing and tissue stiffness must be replicated alongside ...

Ovarian cancer has long proved difficult to treat. Could the answer lie within the disease itself? Discover how synthetic ...

As therapeutic antibodies become more complex, where is the field making real progress and which problems are proving hardest ...

Stanford University researchers have demonstrated that stem cell-derived vascular organoids can regenerate damaged ...

A repurposed small molecule originally developed for spinal cord injury has demonstrated the ability to address multiple ...

A newly identified experimental compound, XL20, has demonstrated neuroprotective effects in mouse models and human motor ...

Preclinical findings from Genespire and SR-TIGET suggest a single administration of a liver-directed lentiviral gene therapy ...