When a bacterial ribosome encounters a defective mRNA during the course of protein synthesis, the ribosome may 'stall', thereby blocking further protein synthesis at that ribosome. Such a stalled ...

Fatal errors sometimes occur in messenger RNA, the blueprint for proteins. A special form of RNA, so-called tmRNA, bypasses these errors and cleans up the mess. Dutch researcher Sharief Barends ...

Ribosomes are “protein factories” in the cells of all living things. They produce proteins based on existing genetic codes stored on special nucleic acid molecules. These molecules, also called ...

The molecular processes responsible for protein synthesis are usually very efficient, but the ribosomes can stall if defective or incomplete mRNA molecules dock and initiate translation. To rescue ...