A deadly tornado outbreak ripped through Missouri, Arkansas and Mississippi overnight Friday, leaving destruction, power outages and tragic loss in its wake.

At least 15 people are dead in Missouri and Arkansas following a widespread and dangerous severe weather outbreak Friday evening after numerous tornadoes were spotted across multiple states, causing significant damage.

Tornadoes hit the US Midwest and Southeast overnight, killing three in Missouri and causing widespread damage. Forecasters warn of a “high risk” threat for Mississippi and Alabama as storms intensify.

Millions of Americans across the country are on alert for a severe weather outbreak as violent, long-track tornadoes with damaging winds of up to 80 mph and large hail are expected across the Midwest and South with the cross-country storm moveing east.

Large and destructive tornadoes are carving paths of destruction across the South for the second day in a row.

Meanwhile, the severe weather threat will linger through Sunday from Florida northward into the upper Ohio River Valley, forecasters warned.