The week’s biggest news for Wall Street is likely arriving on Friday, when Federal Reserve Chair Jerome Powell will give a highly anticipated speech in Jackson Hole, Wyoming. The setting has been home to big policy announcements from the Fed in the past, and the hope on Wall Street is that Powell will hint that an interest rate cut is coming soon.

U.S. stocks are falling again, this time after the country’s largest retailer reported profits that came up short of Wall Street’s expectations. The S&P 500 fell 0.5% in early trading Thursday and was on track for a fifth straight modest loss since setting an all-time high last week.

For the quarter to July 31, Walmart’s adjusted earnings per share, which excludes nonrecurring items, rose to 68 cents from 67 cents in the same period a year ago, to miss the average analyst EPS estimate compiled by FactSet of 73 cents.

NEW YORK (AP) — U.S. stock indexes are edging lower on Thursday as Wall Street makes its final moves before the head of the Federal Reserve gives a highly anticipated speech on Friday that could hint at where interest rates are going.

This week's set-piece event is the Jackson Hole central-bank gathering in Wyoming, slated for Thursday through Saturday. Investors will tune into Federal Reserve Chair Jerome Powell's speech for any h