Metabolic networks constitute the complex web of biochemical reactions that sustain cellular life, integrating enzymes, substrates, and regulatory elements. Systems biology provides the framework to ...
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Metabolic network simulations reveal potential gene targets to re-sensitize drug-resistant breast cancer
The team first constructed cell-specific metabolic network models by integrating proteomic data obtained from two different types of drug-resistant MCF7 breast cancer cell lines: one resistant to ...
Glucolipid metabolism is a core biological process for maintaining energy balance and homeostasis in the human body. However, the widespread adoption of ...
Two papers published today in the journal Nature describe a significant advance in understanding the complex functions of the metabolic network. The research is from the lab of Marian Walhout, PhD, ...
Two new papers describe a significant advance in understanding the complex functions of the metabolic network. Two papers published today in the journal Nature describe a significant advance in ...
Mitochondrial dysfunction manifests as structural damage (swelling, cristae rupture, increased volume/decreased numerical density), energy metabolism abnormalities (reduced COX and Complex I-III ...
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