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Activation-Induced Cytidine Deaminase (AID): An enzyme that catalyses the deamination of cytosine bases in DNA, initiating both somatic hypermutation and class switch recombination in B cells.
Tumor-infiltrating B cells (TIL-Bs) within TLS contribute to improved patient survival and immunotherapy responses by facilitating antibody class switching, somatic hypermutation, and cytokine ...