The San Francisco 49ers have a better record than the Houston Texans, but the oddsmakers have the Texans as favorites. They ...

Quarterback Brock Purdy will miss his fourth straight game for the San Francisco 49ers because of a toe injury.

Thanks to coordinator Robert Saleh, the San Francisco 49ers have fielded an effective defense despite devastating injuries.

San Francisco 49ers fans received very promising news on star wide receiver Brandon Aiyuk. According to San Francisco ...

Facing a team with a 2-4 record would typically be favorable the San Francisco 49ers. However, the Houston Texans aren't a ...

Meanwhile, the Texans haven't been as fortunate to begin the 2025 campaign. Houston has started 2-4 and is fresh off a 27-19 ...

Head coach Kyle Shanahan on Friday told reporters wide receiver Brandon Aiyuk is making progress toward a return that could ...

With starter Brock Purdy slowly working his way back from the right big toe injury that's kept him out since Week 4, the ...

The 49ers' top quarterback has missed five of seven games this season so far. Here's the latest on his status for Week 8.

The San Francisco 49ers will be without two key offensive starters once again as they take on an excellent Houston Texans ...

In his absence, Matt Hennessy projects to start at center Sunday at Houston.

San Francisco 49ers quarterback Brock Purdy has been ruled out for his team's Week 8 matchup against the Houston Texans amid ...