CuraSen Therapeutics has commenced its Phase IIa proof-of-concept trial of CuraAX (CST-3056) with dosing of the first patient ...

A study conducted by researchers at the Center for Redox Processes in Biomedicine (Redoxoma) has shown that ATP-sensitive ...

A dangerous animal sedative called Xylazine is causing a crisis in the US and UK. Often mixed with fentanyl, it intensifies ...

Phenylephrine is an alpha 1‐adrenergic receptor (α1R) agonist. Evidence indicates activation of α1Rs can initiate both vasoconstrictor and dilator signaling. How phenylephrine affects cerebrovascular ...

In this phase 3, multinational, randomized, double-blind trial, we examined the safety and efficacy of once-daily orforglipron at doses of 6 mg, 12 mg, or 36 mg, as compared with placebo (assigned in ...

HOUSTON -- Patients with polycythemia vera (PV) and a history of treatment with GLP-1 agonists had significantly lower rates of multiple adverse outcomes associated with the disease, a large ...

ABSTRACT: With an estimated 20.5 million deaths from cardiovascular diseases (CVDs) in 2021, around 80% of these deaths will occur in low- and middle-income countries, making CVDs the leading cause of ...

Psoriasis and psoriatic arthritis (PsA) are chronic, immune-mediated inflammatory diseases associated with several shared common comorbidities, of which obesity is one of the most prevalent. A complex ...

Skeletal muscle development and adaptation are governed by complex regulatory networks that coordinate gene expression, signaling pathways, and intercellular communication. Among the emerging key ...

Shivering after general anaesthesia is common. As well as being unpleasant for the patient, it can increase pain and affect oxygen levels. Alpha-2 (α-2) adrenergic agonists are a group of drugs that ...