For decades, biologists have known that the instructions for life are written in DNA, yet the vast majority of those letters seemed to sit in the dark, doing little that was obvious. Now a new ...
Researchers showed that in C. elegans, the protein MBD-2 regulates genes through repressive histone marks rather than DNA ...
Researchers at the School of Biological Sciences of The University of Hong Kong (HKU) have uncovered how eukaryotic cells can ...
The discovery of catalytic RNA transformed our understanding of life's beginnings. Clare Sansom explores how the RNA world ...
Researchers at the School of Biological Sciences of The University of Hong Kong (HKU) have uncovered how eukaryotic cells can ...
Figure 1. Dual binding patterns of MBD proteins in mammals and in C. elegans.In mammals (left), previous studies show that most MBD3 binding sites ...
Upregulated expression of transcription factors promoting cone identity in late-stage retinal progenitors drives development ...
Life runs on instructions you never see. Every cell reads DNA, turns that message into RNA, and then builds proteins that ...
Among them was David Liu, a biochemist at the Broad Institute and Harvard University in Cambridge, Massachusetts. Liu isn’t a ...
When scientists sequence tumor DNA, they typically find small amounts of genetic code from bacteria, viruses and fungi – microorganisms that, if actually present in tumor tissues, could influence how ...
Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective, the new gene must make it into a cell's nucleus. The ...