Several bacteria from the Clostridium genus produce botulinum neurotoxins—the most potent biological toxins known—that cause botulism by blocking neurotransmitter release from nerves. Typically, the ...

UPTON, NY -- By deciphering the near atomic-level structure of the catalytic domain of botulinum toxin type E -- one of seven neurotoxins that cause botulism, a disease that paralyzes victims by ...

Researchers at Stockholm University have succeeded in creating a molecular blueprint of how one of the world's most dangerous toxins, botulinum toxin, is structured, stabilized, delivered and released ...

The toxin complex with its 14 components. The toxin itself is colored pink and sits at the top of the complex. The structure consists of tens of thousands of atoms, and here we only show the surface ...

Researchers at the Center for Life Sciences at the Paul Scherrer Institute PSI have for the first time identified structural changes in the botulinum neurotoxin, botox for short, that are believed to ...

In a comprehensive research study, scientists have uncovered a previously unknown mechanism explaining how neurons survive botulinum neurotoxin type A (BoNT/A) exposure, despite the toxin's powerful ...

The Botox injections that smooth wrinkles rely on the ability of botulinum toxins from the bacterium Clostridium botulinum to block communication between cells. In the cosmetic treatment, these toxins ...

Researchers have identified genes encoding a previously undiscovered version of the botulinum neurotoxin in bacteria from a cow’s gut. Researchers from the Quadram Institute have identified genes ...

Foodborne botulism is a potentially deadly condition that’s caused by eating food contaminated with botulinum toxin, a potent toxin that attacks the body’s nervous system. The disease is incredibly ...

Local injections of botulinum toxin type A have been used to treat essential head tremor but have not been extensively studied in randomized trials. In a multicenter, double-blind, randomized trial, ...