In a study, blocking the immune system complement protein C3 was shown to reduce MS disease severity in older mice but not in ...

(Left) Pre-ignition (below the activation threshold) Only a handful of immune “tags” (C3b proteins) cover the nanoparticle, so it barely sticks to the white membrane—too few contact points means the ...

Leveraging human organoid-based mechanistic investigation, researchers reveal how an immunosuppressive drug, antithymocyte ...

Researchers discovered a previously unknown mechanism that may drive tissue damage and a new target for drug discovery. Our immune system is armed with an array of defenses designed to detect and ...

Medically reviewed by David Ozeri, MD Complement 3 glomerulopathy (C3G) is a rare kidney disorder—in many cases, the exact cause is unknown.Possible C3G causes include genetic mutations, ...