A method for arrayed CRISPRi screening in organoids enables the investigation of morphogenesis in human stem cell-derived tissues, revealing the roles of ZIC2, SOX11, and ZNF521 in neural tube closure ...
Two separate research teams used base editing to make single-nucleotide changes in human embryos this month, targeting genes ...
For now, that goal remains elusive. The lab-grown cells stopped developing at an immature stage. Many hurdles need to be ...