Animals depend on their sense of smell to locate food, identify mates and evade danger. In mammals, olfactory perception typically relies on G protein–coupled receptor (GPCR) pathways. Insects, by ...

Adhesion GPCRs are a large class of surface proteins that recognize chemical and mechanical stimuli in the body. The rapidly expanding body of knowledge on the therapeutic targeting of these receptors ...

Illustration of small molecule modulation of β-arrestins and GPCR signaling pathways based on concepts developed by the Lefkowitz Laboratory, Duke University. To function normally, nearly every cell ...

To function normally, nearly every cell in the human body relies on G-protein coupled receptors (GPCRs) to receive and send signals. That's why GPCRs are targeted by roughly one-third of all ...

University of Michigan researchers have developed a new tool to better understand how chemicals like dopamine and epinephrine interact with neurons. These chemicals are among a wide variety of signals ...