A preprint describing genetically edited human embryos is raising concerns among scientists that the U.S. is becoming more accepting of using gene editing to enhance embryos. “The cat’s out of the bag ...

MIT scientists have found a way to make gene editing far safer and more accurate — a breakthrough that could reshape how we treat hundreds of genetic diseases. By fine-tuning the tiny molecular “tools ...

Physician and molecular biologist Katherine High remembers sitting at a staff meeting of the gene therapy company Spark Therapeutics on November 15, 2018, waiting to hear from a guest speaker, when ...

The US Food and Drug Administration on Thursday approved the first gene therapy for inherited hearing loss, a one-time treatment that proved to be life-changing for a small number of children in a ...

An experimental gene therapy appears safe and highly effective for restoring hearing to people born with a rare form of deafness, researchers reported Wednesday. The study, the largest and longest to ...

In back-to-back studies published in Nature, researchers from Purdue University and Columbia University report a naturally evolved gene-editing system that can activate genes, offering an advantage ...

The authors describe the scientific foundations of a study of gene therapy for hearing loss caused by damaging variants in the gene OTOF. Department of Otorhinolaryngology and Head and Neck Surgery, ...

Diet can leave lasting epigenetic marks that reshape gene expression, metabolic pathways, and disease susceptibility across the lifespan. These diet-driven molecular changes may create a form of ...

In 2018, a nervous-looking He Jiankui took the stage at a scientific conference in Hong Kong. A hush settled over the packed auditorium as the soft-spoken Chinese scientist adjusted his microphone and ...

NASHVILLE—AK Okereke had just finished the 20-minute walk back to his dorm building from Cornell’s Newman Arena when he realized that he’d just made a freshman mistake. Okereke had left his ID in his ...

A new CRISPR breakthrough shows scientists can turn genes back on without cutting DNA, by removing chemical tags that act like molecular anchors. The work confirms these tags actively silence genes, ...

With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to increased knowledge about gene regulation in human cells. How genes are turned on ...