A major medical milestone took place in May 2025, when doctors at the Children’s Hospital of Philadelphia used CRISPR-based gene editing to treat a child with a rare genetic disorder. Unlike earlier ...

Microbes move across the planet, linking ecosystems and spreading genes that shape antibiotic resistance, health, and ...

Thanks to increasingly efficient and affordable gene sequencing technologies, we can now chart our genetic blueprint in unprecedented detail. But what does each gene do? Of the roughly 20,000 genes ...

A new resource from the Gene Ontology Consortium, a comprehensive encyclopedia of the known functions of all protein-coding human genes, has been completed and released on a new website. For the first ...

Most research in human genetics has historically focused on people of European ancestries—a long-standing bias that may limit the accuracy of scientific predictions for people from other populations.

Thousands of previously “invisible” microproteins—tiny chains of fewer than 100 amino acids—can profoundly change human biology when mutated. A fundamental discovery is overturning decades of ...

Putting the uniquely human version of a certain gene into mice changed the way that those animals vocalized to each other, suggesting that this gene may play a role in speech and language. Mice make a ...

The Indigenous peoples of the Bolivian highlands are survivors. For thousands of years they have lived at altitudes of more than two miles, where oxygen is about 35 percent lower than at sea level.

Euan Ashley's lab explores the intricate interactions of gene variants. Tiny "typos," or genetic mutations, can sneak into segments of DNA. Many of these are harmless, but some can cause health ...