In most modern cells, DNA stores the genetic blueprint, and proteins replicate, repair and build from those blueprints. At ...

Type 2 diabetes can turn immune cells that help with tissue repair and anti-inflammatory responses into triggers of chronic inflammation. A recent study investigated why people with type 2 diabetes ...

Spinal cord injury (SCI) is a disabling central nervous system injury that can lead to permanent loss of motor and sensory function below the level of injury. Currently, symptoms are primarily ...

Focal post-traumatic cartilage lesions frequently progress to early osteoarthritis, highlighting the limited regenerative capacity of adult articular cartilage. Compared to native tissue, conventional ...

Unveiling a cellular mechanism by which muscle stem cells repair damage, researchers spark hope for remedying muscle loss caused by injury, aging and weight-loss medications. A team of scientists from ...

Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic tangles overwhelm normal repair pathways, cells flip on a fast but error-prone ...

Over the course of evolution, the human heart has largely lost its ability to regenerate. Our distant ancestors were not afflicted by heart attacks—a condition that emerged primarily with modern ...

Cells age for many reasons, but one idea keeps resurfacing. As the years pass, small DNA changes stack up inside tissues and slowly tilt biology off balance. A new set of analyses points the finger at ...

When a cell divides, a small section of the telomere of each chromosome is worn away. While most cells use the enzyme telomerase to mitigate this loss, about 10–15% of cancers use a different ...

The DNA of human cells consists of a sequence of about 3.1 billion building blocks. Cells go to great lengths to maintain the integrity of this vast store of information. They constantly untangle ...