Low-dose opioid therapy provides stable, long-term symptom control and dose stability for patients with augmented restless legs syndrome.

"Year to date" sales for 2022, 2023, 2024, and 2025 sales are shown in series at the top of the table and then just below a comparison of 2025 versus 2024 and 2025 versus 2023 is displayed. This ...

Researchers at USF Health have discovered a new way opioid receptors can work that may lead to safer pain medications. Their findings show that certain experimental compounds can amplify pain relief ...

Opioids, such as oxycodone, morphine, codeine, tramadol and fentanyl, are commonly prescribed to manage pain. You might be given a prescription when experiencing pain, or after surgery or an injury.

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

Tramadol, a potent synthetic opioid, has been widely used to treat moderate to severe pain, but a new study suggests that the medication’s potential risks outweigh its “limited” benefits for chronic ...

Lev Facher covers the U.S. addiction and overdose crisis. The Food and Drug Administration will soon require prescription opioid manufacturers to include stronger language on the medications’ labels ...

In effort to slow the opioid crisis, federal regulators plan to restrict a kratom compound available in smoke shops over the counter in Spokane and across the country. The Food and Drug Administration ...

Jerry Abrams, a 64-year-old marketing strategist in Minneapolis, used to run marathons. But two decades of degenerative spine disease have left him unable to run — and he's grieving. For Abrams, ...

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