IPA, a non-coding RNA from the CUL1 gene that stabilizes the nucleolus and supports ribosome production. Removing it ...
For decades, biologists have known that the instructions for life are written in DNA, yet the vast majority of those letters seemed to sit in the dark, doing little that was obvious. Now a new ...
A signal-processing–based framework converts DNA sequences into numerical signals to identify protein-coding regions. By integrating spectral ...
Deep-learning model decodes the regulatory effects of DNA changes ...
Scientists at the Children's Medical Center Research Institute at UT Southwestern (CRI) report that inactivating a certain protein-coding gene promotes liver tissue regeneration in mammals. "This ...
With the help of a technique called Massively Parallel Ribosome Profiling (MPRP), Shira Weingarten-Gabbay and colleagues identified more than 4000 open reading frames (ORFs) across 679 ...
Nucleic acid-based therapeutics, including antisense oligonucleotides (ASO), small interfering RNA (siRNA), messenger RNA (mRNA), immunomodulatory DNA/RNA, and gene-editing guide RNA (gRNA), hold ...