The discovery could pave the way for a groundbreaking RNA-based multi-cancer treatment. Alternative RNA splicing functions ...
Researchers have discovered that cancer cells suppress 'poison exons' -- genetic elements that act as an off switch for protein production -- in a key gene called TRA2 , promoting tumor growth. By ...
However, when cancer rewrites the script ... see if they could increase the inclusion of the poison exon in the TRA2β gene ...
However, when cancer rewrites the script ... inclusion of the poison exon in the TRA2β gene and reactivate the kill switch. They found their answer in antisense oligonucleotides (ASOs ...
Synthetic ‘kill switch’ could fast track new immunotherapies, turning bacterial armies against cancer tumours, study shows.
A study reveals how cancer disrupts RNA splicing and presents a potential therapy using antisense oligonucleotides to target ...
Cells have a natural editing system that allows them to rearrange genetic instructions to create different proteins from the ...