The story of the cell cycle is often told only through the perspective of the chromosomes as they replicate and then divide. This resource beautifully illustrates the role of the cytoskeleton in that ...
Over the past two decades, researchers have learned that DNA inside the cell nucleus naturally folds into a network of ...
If you took high school biology, you probably learned about cell division: a crucial process in all life forms officially called mitosis. For over one hundred years, students have learned that during ...
Before cells can divide by mitosis, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Scientists have until now ...
Researchers have discovered how proteins work in tandem to regulate 'treadmilling', a mechanism used by the network of microtubules inside cells to ensure proper cell division. Researchers at the ...
As the cell proceeds through the stages of cell division (from left to right: interphase, prometaphase, metaphase, and anaphase), chromosomes become progressively more compact through a combination of ...
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How chromosomes shape up for cell division: Scientists reveal DNA loop formation mechanisms
Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA—its genome—and segregate it equally ...
Timelapse of a gene-edited medaka fish embryo undergoing mitosis. The mitotic spindle – the green strands in the middle of the cells – can be seen aligning and segregating duplicated chromosomes, ...
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A starting signal for cell division: Molecular switch ensures that cells divide at the right time
About 100 cells divide every second in our body. A key protein in cell division is a protein kinase termed Plk1, because it activates other proteins involved in this process. Plk1 is also ...
Researchers at the Max Delbrück Center and the University of Oxford have found that a cellular housekeeping function called autophagy—by which cell components are broken down and recycled—plays a ...
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