GEN - Genetic Engineering and Biotechnology News

Protein Design’s AI Revolution: Inside David Baker’s “Communal Brain”

I have this idea of a communal brain.” David Baker, PhD, told me as I sat in his office at the University of Washington (UW) ...

AI helps scientists improve prediction of which DNA sequences bind to each other

Researchers have demonstrated a novel AI model that can predict which DNA molecules bind with other DNA molecules. A more ...

DNA origami turns secret messages into nano–Morse code that acts as multiplayer molecular encryption

Mathematics has always been at the core of securing information. From online banking to government communications, modern ...
eLife

In silico design and validation of high-affinity RNA aptamers for SARS-CoV-2 comparable to neutralizing antibodies

Computer-Aided Aptamer Modeling and Optimization (CAAMO) enables structure-guided RNA aptamer affinity maturation, producing a SARS-CoV-2 RBD (receptor binding domain) binder that rivals neutralizing ...