Facing a team with a 2-4 record would typically be favorable the San Francisco 49ers. However, the Houston Texans aren't a ...

Quarterback Brock Purdy will miss his fourth straight game for the San Francisco 49ers because of a toe injury.

The San Francisco 49ers enter Week 8 facing renewed questions about the health of their starting quarterback, Brock Purdy.

The San Francisco 49ers have a better record than the Houston Texans, but the oddsmakers have the Texans as favorites. They ...

The Houston Texans will be without Nico Collins for Sunday's game against the San Francisco 49ers. Jayden Higgins and Jaylin ...

Saleh might have been the 49ers' top offseason acquisition, and no NFL assistant coach has made a bigger impact this season.

Preview the NFL week 8 matchup between the Houston Texans and 49ers, including betting odds, tips, trends, and game ...

This article was originally published on www.si.com/nfl/49ers as The San Francisco 49ers could be on the brink of a lineup ...

Find single game tickets to the Houston Texans vs. San Francisco 49ers NFL Week 8 matchup on Sunday, October 26, 2025 at NRG ...

Sunday, 1 p.m. EDT, FOX. BetMGM line: 49ers by 1 ½. Against the spread: 49ers 4-3, Texans 2-4. Series record: 49ers lead 4-1.

San Francisco sits at 4-2 but mounting injuries have hurt the team's chances in 2025. Here are five trade targets who could ...

The shorthanded San Francisco 49ers shocked the Atlanta Falcons in Week 7 NFL action on Sunday Night Football.