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This study presents valuable findings by demonstrating that specific GPCR subtypes induce distinct extracellular vesicle miRNA signatures, highlighting a potential novel mechanism for intercellular ...
The efficiencies with which activated B lymphocytes proliferate and develop into antibody (Ab)- secreting plasma cells are critical determinants of adaptive humoral immunity and central to sustaining ...
Optimised genome editing for precise DNA insertion and substitution using Prime Editors in zebrafish
This study presents a valuable comparison of the efficiency and precision of two prime editing methods to introduce single-nucleotide variants and longer exogenous DNA sequences into the zebrafish ...
A population of ischemia-induced newborn astrocytes, positive for Thbs4, that migrate to the lesion border, where they produce and degrade hyaluronan, modulating the local extracellular matrix, has ...
Wide-gauge posture in the limb skeleton of Titanosauriformes is an exaptation to gigantism, as it is not correlated with body size in deeply branching titanosaurs.
The study presents valuable theoretical insights by attempting to classify pattern-forming gene subnetworks and exploring their potential mechanisms. However, the results are incomplete, as they rely ...
This valuable study provides solid evidence that MgdE, a conserved mycobacterial nucleomodulin, downregulates inflammatory gene transcription by interacting with the histone methyltransferase COMPASS ...
The study provides valuable technical advances to generate and isolate neural rosettes. The technique is robust, as indicated by both reviewers. The evidence is solid, as shown in orthogonal ...
Studying the growth of bacteria without cell walls in an artificial environment can shed new light on the proliferation of primitive life-forms billions of years ago.
In this episode, we hear about parasites as molecular matchmakers, drug combinations and cancer treatment, chemical defences in poison frogs, the impact of education on brain structure, and what ...
eLife works to improve research communication through open science and open technology innovation ...
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