If the 49ers win Sunday in Houston, they'll match their overall win total from last season and they'll be alone atop the NFC ...

The 49ers could open wide receiver Brandon Aiyuk's 21-day practice window as soon as next week, coach Kyle Shanahan said Friday."Yeah, I believe ...

The San Francisco 49ers got extremely lucky finding Eddy Pineiro after the year started. He's been even better than Kyle Shanahan thought ...

George Kittle praises Robert Saleh as the team's best-ever signing, crediting his energy and leadership for San Francisco's ...

Bleacher Report contributor Brad Gagnon recently named every NFL team's most disappointing player so far this season, and his ...

San Francisco 49ers head coach Kyle Shanahan remains hopeful that cornerback Deommodore Lenoir will be ready to play on ...

The San Francisco 49ers will be without two key offensive starters once again as they take on an excellent Houston Texans ...

San Francisco 49ers head coach Kyle Shanahan spoke to reporters following Friday's practice, providing final updates ahead of ...

With starter Brock Purdy slowly working his way back from the right big toe injury that's kept him out since Week 4, the ...

Head coach Kyle Shanahan revealed that the San Francisco 49ers could—with emphasis on could—open the practice window for wide receiver Brandon Aiyuk as early as next week. However, nothing is ...

Brock Purdy has been ruled out again this week. Purdy was a limited participant in practice this week, but the 49ers ruled him out with ...