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Preview the Aug. 21 matchup between the Minnesota Twins and Athletics with odds over/under, game spread, betting lines and more.

The A's (57-70) visit the Minnesota Twins (58-67) for the second game of their 3-game series Wednesday. First pitch from Target Field is set for 7:40 p.m. ET. Let's analyze BetMGM Sportsbook's MLB odds around the A's vs.

The Twins kept the pressure on with aggressive baserunning from their younger players, but an inability to come up with hits with runners in scoring position continues to plague the team.

Shea Langeliers hit his 27th home run, Tyler Soderstrom extended his hitting streak to 17 games and the Athletics beat the Minnesota Twins 6-3 on Tuesday night.

Pregame analysis and predictions of the Athletics vs. Minnesota Twins MLB game to be played on August 20, 2025 on ESPN.