Liddle Syndrome Liddle syndrome is an autosomal dominant disorder caused by hyperactivity of the amiloride-sensitive sodium channel (ENaC) of the principal cell of the cortical collecting tubule.

Sep 25, 2025 · Oral vitamin B12 halves the rate of moderate-to-severe capecitabine-induced hand-foot syndrome in patients with breast cancer.

This syndrome is characterized by short stature, intellectual impairment, dental abnormalities, muscle weakness, severe hypertension by the third decade of life, low fractional excretion of sodium ...

Jan 29, 2025 · When looking at all-cause mortality, rates in patients with Lynch syndrome are comparable with those in the general population.

Jul 11, 2025 · Dr Rachel Rubin speaks with Dr Melissa Kaufman and Dr Una Lee, co-chairs of the new AUA/SUFU/AUGS guideline on genitourinary syndrome of menopause.

Aug 13, 2025 · Learn how to recognize the various overlapping conditions with Ehler-Danlos syndrome and tailor multidisciplinary care to improve patient outcomes.

(C) Liddle syndrome. Mutations in the β- or γ-subunit of the ENaC prevent binding to Nedd4, a repressor factor, leading to constitutive expression of sodium channels, volume expansion and ...

Dec 22, 2025 · The first dose of the COVID vaccine AZD1222 is associated with an increased risk for thrombotic thrombocytopenia syndrome; however, no such association is observed with any dose of …

Jun 18, 2025 · The combination of leflunomide and hydroxychloroquine outperformed placebo in reducing disease activity in primary Sjögren syndrome in a second phase II study.

Severe or decompensated obstructive sleep apnoea syndrome is associated with lower total testosterone levels in men with severe obesity, and CPAP can improve testosterone levels …