UniProt is the world’s leading high-quality, comprehensive and freely accessible resource of protein sequence and functional information.

The UniProt Knowledgebase (UniProtKB) is the central hub for the collection of functional information on proteins, with accurate, consistent and rich annotation.

The UniProt databases are the UniProt Knowledgebase (UniProtKB), the UniProt Reference Clusters (UniRef), and the UniProt Archive (UniParc). The UniProt consortium and host …

The unreviewed UniProtKB/TrEMBL database will be reduced in size in release 2026_02 (first half of 2026). Entries to be retained in UniProtKB: Entries from reference proteomes All reviewed …

UniProt proteomes may include both expertly reviewed (UniProtKB/Swiss-Prot) and unreviewed (UniProtKB/TrEMBL) entries. The proportion of reviewed entries varies between proteomes, …

The UniProt Archive (UniParc) is a comprehensive and non-redundant database of protein sequences. These sequences are sourced from public sequence databases, and each unique …

Select all cross-references to external databases of the category '3D structure databases' of UniProtKB entries that are classified with the keyword 'Acetoin biosynthesis (KW-0005)' …

All proteomes will remain accessible in the Proteomes database. Entries removed from unreviewed UniProtKB/TrEMBL will remain accessible in the UniParc sequence archive.

The UniProt Archive (UniParc) is a comprehensive and non-redundant database of protein sequences. These sequences are sourced from public sequence databases, and each unique …

UniProt is updated roughly every eight weeks. You can download small data sets and subsets directly from this website by following the download link on any search result page.