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Why is Fiorinal controlled while Fioricet is sometimes controlled? The answer comes down to a decades-old federal exemption that still affects pharmacy practice today. Both medications contain butalbital, but because of a regulatory exemption dating back to the 1960s, certain butalbital combination products were exempted from federal controlled substance scheduling if they met specific criteria. As a result, Fiorinal is federally scheduled, while some Fioricet products qualify for the exemption
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